Aridhia DRE - Trusted Research Environment

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Consideration of the Root Causes in Candidate Attrition During Oncology Drug Development

Oncology candidates fail at twice the rate of other therapeutic areas. This paper examines root causes of attrition from first-in-human through to registration.

Crowdsourcing proposal supporting patient engagement in parkinsons disease a digital research environment dre enabled patient swarm approach to develop qsp models

How a DRE-enabled patient swarm approach incorporates the patient voice into collaborative QSP model development for Parkinson's disease across academic centres

Artificial Intelligence Opportunities to Guide Precision Dosing Strategies

How AI guides precision dosing, therapeutic drug monitoring, biomarker integration and individualised pharmacotherapy. Published J Pediatr Pharmacol Ther, 2024.

Unlocking the mysteries of rare disease drug development a beginners-guide for clinical pharmacologists

A beginner's guide for clinical pharmacologists entering rare disease drug development. Published in Clinical and Translational Science, 2025

The GOSH Aridhia DRE Partnership

How GOSH and Aridhia partnered in 2017 to build a state-of-the-art Digital Research Environment, now supporting 400+ active research and clinical projects.

Data federation in a trusted research environment

This whitepaper covers the concept of data federation within a trusted research environment by using the example of Aridhia’s work with the PHEMS consortium.

DARE UK TREvoultion Interim Report

This interim report details initial work carried out by Aridhia under the DARE UK TREvolution project.

Implementing precision medicine with the Liver Cancer Collaborative

How the Liver Cancer Collaborative implemented precision medicine using the Aridhia DRE. A blueprint for governed, collaborative cancer research delivery.

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